The purpose of the Request for Information (RFI) is to solicit public input on 1) a set of minimum core common data elements (CDEs) that would be used across all NIH funded/conducted clinical studies/trials and community-based research involving human participants; 2) additional CDEs for social determinants of health (SDoH) and clinical domains including autoimmune diseases and immune-mediated diseases; and 3) technologies, tools and policies that could facilitate the use of NIH CDEs.  NIH CDEs are defined as CDEs “recommended” or “required” by an NIH body, and/or found in the NIH CDE Repository. These RFI responses will be used to inform NIH’s continuing guidance on CDE use and assist in the planning for adequate resources for CDE implementation. Refer to the article for more information.