Notice NOT-HL-24-008 informs potential applicants of the new National Heart, Lung, and Blood Institute (NHLBI) SBIR/STTR programs policies regarding total funding support (i.e., the sum of direct costs, indirect costs, and fee) for grant applications that exceed the NIH-wide budget guidelines set by the U.S. Small Business Administration (SBA). The current NIH-wide budget guidelines for the SBIR and STTR programs may be found at https://seed.nih.gov/small-business-funding/small-business-program-basics/understanding-sbir-sttr#Budget-and-timelines-for-funding.