NIH expects grant applications to generally describe all proposed methods and present all preliminary data within the scientific narrative in the form of text, tables, and figures. However, NIH understands that, in certain situations, the use of video technology can be critical in conveying key aspects of a grant application. The purpose of Notice NOT-OD-24-067 is to provide policy and guidelines for investigators submitting videos to accompany their NIH applications. Notice NOT-OD-24-067 replaces the Video formats instructions in NIH Guide Notices NOT-OD-12-141 and NOT-OD-20-061, and referenced in NIH Grants Policy Statement Section 2.3.7, and revises the related portion of the NIH Guide Notice NOT-OD-19-083 on post-submission application materials.